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Nervous coordination and skeletal muscles GapFill
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The nervous system uses to pass electrical impulses around the body. At rest, the inside of an axon is more negatively charged than the outside, but when a stimulus generates , the membrane is depolarised and voltage-gated ion channels cause an influx of ions. The membrane is repolarised by moving ions back out of the membrane. In myelinated neurones, impulses can only pass between , which lack Schwann cells. This is called .
Signals are passed across synapses using . At cholinergic synapses, is stored in in the presynaptic knob and can diffuse across the synaptic cleft to bind to receptors on the postsynaptic membrane, which passes the signal to the next neurone. A similar mechanism is used in to initiate the contraction of skeletal muscles.
Skeletal muscles are made from bundles of , which contain different types of filament. filaments have globular heads bound to ADP. These can bind to filaments only when moves out of the way of the binding sites in response to the action of .