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Neuronal communication GapFill
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The nervous system consists of a series of interconnecting pathways which respond to changes in the environment, called . Pathways generally consist of a receptor, a and an effector. The nervous system uses to pass electrical impulses around the body.
At rest, the inside of an axon is more than the outside, but when a stimulus generates , the membrane is depolarised. may also be generated by the sideways movement of ions along a neurone towards areas of lower concentration.
A Pacinian corpuscle changes its permeability to ions when it is stretched, and voltage-gated ion channels cause an influx of the ions when a generator potential is created. The membrane is repolarised by moving ions back out of the membrane.
In myelinated neurones, impulses can only pass between , which lack Schwann cells. This is called .
Signals are passed across synapses using . At cholinergic synapses, is stored in in the presynaptic knob and can diffuse across the synaptic cleft to bind to receptors on the postsynaptic membrane, which passes the signal to the next neurone.